Randomization for concealment.
نویسنده
چکیده
منابع مشابه
Eliminating bias in randomized controlled trials: importance of allocation concealment and masking.
Randomization in randomized controlled trials involves more than generation of a random sequence by which to assign subjects. For randomization to be successfully implemented, the randomization sequence must be adequately protected (concealed) so that investigators, involved health care providers, and subjects are not aware of the upcoming assignment. The absence of adequate allocation concealm...
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2. The authors’ assertion: “computer-generated block randomization done independently by the USA based study statistician” is not found either in the Supplementary data [1] or the published trial protocol [2]. The published paper [1] states that the external statistician performed allocation concealment (and not random sequence generation). The Commentary [3] already reported that allocation co...
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BACKGROUND Randomized controlled trials (RCTs) which are of poor quality tend to exaggerate the effect estimate and lead to wrong or misleading conclusions. The aim of this study is to assess the quality of randomization methods, allocation concealment and blinding within traditional Chinese medicine (TCM) RCTs, discuss issues identified for current TCM RCTs, and provide suggestions for quality...
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Background & Aim: Randomized clinical trials (RCTs) are studies which are able to provide the most valid evidence to compare various interventions in health research. Biases can affect the quality of research and ultimately make the results of a study invalid. One of the most important biases is selection bias. The best way to reduce selection bias is the use of random allocation. The aim of th...
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BACKGROUND AND OBJECTIVES Randomization, allocation concealment, and blind outcome assessment have been shown to reduce bias in human studies. Authors from the Collaborative Approach to Meta Analysis and Review of Animal Data from Experimental Studies (CAMARADES) collaboration recently found that these features protect against bias in animal stroke studies. We extended the scope the work from C...
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Background. This review provides the first methodological information assessment of protocol of acupuncture RCTs registered in WHO International Clinical Trials Registry Platform (ICTRP). Methods. All records of acupuncture RCTs registered in the ICTRP have been collected. The methodological design assessment involved whether the randomization methods, allocation concealment, and blinding were ...
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ورودعنوان ژورنال:
- Journal of the Royal Society of Medicine
دوره 103 2 شماره
صفحات -
تاریخ انتشار 2010